(Rac)-Lys-SMCC-DM1
Product Specifications
UNSPSC Description
(Rac)-Lys-SMCC-DM1 ((Rac)-Lys-Nε-MCC-DM1) is the racemate of Lys-SMCC-DM1 (HY-101982). Lys-SMCC-DM1 is a linker-payload component that has the potential to inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1[1].
Target Antigen
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rac-lys-smcc-dm1.html
Purity
98.18
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@]1([C@@](CC(N(C(C=C2C=C3OC)=C3Cl)C)=O)([H])OC([C@H](C)N(C)C(CCSC(CC4=O)C(N4C[C@@H]5CC[C@@H](C(NCCCC[C@H](N)C(O)=O)=O)CC5)=O)=O)=O)[C@H]([C@@H]([C@](OC6=O)([H])C[C@]([C@](/C=C/C=C(C)/C2)([H])OC)(N6)O)C)O1
Molecular Weight
1103.71
References & Citations
[1]Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101982A/Rac-Lys-SMCC-DM1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101982A/Rac-Lys-SMCC-DM1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Polyclonal CDC37 Antibody [DyLight 550]](https://cdn.genprice.uk/genprice/genprice2.png)
