(S) - (-) -Perillic acid

(S) - (-) -Perillic acid is a terpenoid plant extract with antimicrobial and anticancer activities. (S) - (-) -Perillic acid induces cell apoptosis and cell cycle arrest, and increases the levell of Bax, Bcl2, p21 and caspase-3 proteins. (S) - (-) -Perillic acid can be used for cancer and infection research[1][2][3].

Product Specifications

CAS Number

[23635-14-5]

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Apoptosis; Bacterial

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/s-minus-perillic-acid.html

Purity

95.0

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(C1=CC[C@@H](C(C)=C)CC1)O

Molecular Formula

C10H14O2

Molecular Weight

166.22

Precautions

H315, H319, H335

References & Citations

[1]Ferri N, et al. Effect of S (-) perillic acid on protein prenylation and arterial smooth muscle cell proliferation. Biochem Pharmacol. 2001 Dec 15;62 (12) :1637-45.|[2]Yeruva L, et al. Perillyl alcohol and perillic acid induced cell cycle arrest and apoptosis in non small cell lung cancer cells. Cancer Lett. 2007 Nov 18;257 (2) :216-26.|[3]Khandelia H, et al. Interaction of salicylate and a terpenoid plant extract with model membranes: reconciling experiments and simulations. Biophys J. 2010 Dec 15;99 (12) :3887-94.