Picrasidine Q

Picrasidine Q, an alkaloid component extracted from Angelica keiskei species, has the capacity of anti-cell transformation and anti-cancer. Picrasidine Q induces cell apoptosis and G1 phase arrest in human esophageal cancer cell lines, and directly inhibits FGFR2 kinase activity[1].

Product Specifications

CAS Number

[101219-61-8]

UNSPSC

12352005

Target

Apoptosis; FGFR

Type

Natural Products

Related Pathways

Apoptosis; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/picrasidine-q.html

Solubility

10 mM in DMSO

Smiles

O=C1C(OC)=C(C2=NC=CC3=C2N1C4=CC=CC=C34)O

Molecular Formula

C15H10N2O3

Molecular Weight

266.25

References & Citations

[1]Shi Y, et al. FGFR2 regulation by picrasidine Q inhibits the cell growth and induces apoptosis in esophageal squamous cell carcinoma. J Cell Biochem. 2018;119 (2) :2231-2239.