Picrasidine Q
Product Specifications
UNSPSC Description
Picrasidine Q, an alkaloid component extracted from Angelica keiskei species, has the capacity of anti-cell transformation and anti-cancer. Picrasidine Q induces cell apoptosis and G1 phase arrest in human esophageal cancer cell lines, and directly inhibits FGFR2 kinase activity[1].
Target Antigen
Apoptosis; FGFR
Type
Natural Products
Related Pathways
Apoptosis;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/picrasidine-q.html
Solubility
10 mM in DMSO
Smiles
O=C1C(OC)=C(C2=NC=CC3=C2N1C4=CC=CC=C34)O
Molecular Weight
266.25
References & Citations
[1]Shi Y, et al. FGFR2 regulation by picrasidine Q inhibits the cell growth and induces apoptosis in esophageal squamous cell carcinoma. J Cell Biochem. 2018;119(2):2231-2239.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N9507/Picrasidine-Q-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N9507/
Clinical Information
No Development Reported
CAS Number
101219-61-8
Available Sizes
Curated Selection
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