MmTx2 toxin
MmTx2 toxin is a GABAA receptor modulator that enhances GABAA receptor sensitivity to agonists. MmTx2 toxin can be obtained from venom of coral snake. MmTx2 toxin can be used in the study of neurological diseases such as epilepsy, schizophrenia and chronic pain[1].
Product Specifications
Product Name Alternative
Micrurotoxin 2
UNSPSC
12352209
Target
GABA Receptor
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mmtx2-toxin.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](N)CC(C)C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H]2[C@@H](C)O)=O)[C@@H](C)O)=O)CC3=CC=CC=C3)=O)CCC1)=O)CSSCC(NC2=O)C(N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N5C(C(NCC(NCC(NC(C(NC(C(N[C@H]6[C@H](CC)C)=O)CO)=O)CCC(N)=O)=O)=O)=O)CCC5)=O)CSSC[C@H](NC7=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N8[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]9CC(C)C)=O)CC(C)C)=O)CO)=O)[C@@H](C)O)=O)CC(O)=O)=O)CC%10=CNC=N%10)=O)CO)=O)=O)CC%11=CC=CC=C%11)=O)C)=O)CCC8)=O)CSSC[C@H](NC9=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]%12CC(N)=O)=O)CC(O)=O)=O)CCCNC(N)=N)=O)[C@@H](C)O)=O)CSSC[C@H](NC%12=O)C(N[C@H](C(O)=O)CC(N)=O)=O)=O)=O)CC(N)=O)=O)C)=O)C(C)C)=O)=O)CO)=O)CCC(O)=O)=O)CO)=O)CC(N)=O)=O)CCC4)=O)=O)[C@@H](C)O)=O)CCCCN)=O)CSSC[C@H](NC6=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]7CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)=O)CC%13=CNC=N%13)=O)CC%14=CNC=N%14)=O)CCC(O)=O)=O)CCC(O)=O)=O)CC%15=CNC%16=CC=CC=C%15%16)=O)CCCCN)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CC%17=CC=C(O)C=C%17)=O)=O)[C@@H](C)O
Molecular Formula
C295H450N94O97S10
Molecular Weight
7185.95
References & Citations
[1]Rosso JP, et al. MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity. Proc Natl Acad Sci U S A. 2015 Feb 24;112 (8) :E891-900.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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