OG-L002
OG-L002 is a potent and highly selective LSD1 inhibitor with an IC50 of 0.02 μM. OG-L002 is a potent monoamine oxidases (MAO) inhibitor with IC50s of 1.38 μM and 0.72 μM for MAO-A and MAO-B, respectively. OG-L002 potently inhibits the expression of HSV IE genes[1].
Product Specifications
CAS Number
1357302-64-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Histone Demethylase; HSV; Monoamine Oxidase
Type
Reference compound
Related Pathways
Anti-infection; Epigenetics; Neuronal Signaling
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/og-l002.html
Purity
99.55
Solubility
DMSO : ≥ 100 mg/mL
Smiles
OC1=CC(C2=CC=C([C@@H]3[C@@H](N)C3)C=C2)=CC=C1
Molecular Formula
C15H15NO
Molecular Weight
225.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Liang Y, et al. A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latency. mBio. 2013 Feb 5;4 (1) :e00558-12.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1
Available Sizes
Frequently Asked Questions
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