DBCO-PEG4-NHS ester
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Product Specifications
CAS Number
[1427004-19-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-peg4-nhs-ester.html
Purity
99.0
Solubility
DMSO : 70 mg/mL (ultrasonic)
Smiles
O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCNC(CCC(N2C3=CC=CC=C3C#CC4=CC=CC=C4C2)=O)=O
Molecular Formula
C34H39N3O10
Molecular Weight
649.69
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Thyroid Hormone Receptor alpha (THRA) (NM_003250) Human Recombinant Protein
Monkey TATA Box Binding Protein Associated Factor 1 ELISA Kit
Monkey TATA Box Binding Protein Associated Factor 1 ELISA Kit
