(S) -Carvedilol
(S) -Carvedilol, the S-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (S) -Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX) [1].
Product Specifications
CAS Number
[95094-00-1]
Product Name Alternative
(S) -BM 14190
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/s-carvedilol.html
Purity
99.64
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O[C@@H](CNCCOC1=CC=CC=C1OC)COC2=CC=CC(N3)=C2C4=C3C=CC=C4
Molecular Formula
C24H26N2O4
Molecular Weight
406.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Wu T, et al. Protective effects of S-carvedilol on doxorubicin-induced damages to human umbilical vein endothelial cells and rats. J Appl Toxicol. 2019 Aug;39 (8) :1233-1244.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor
Available Sizes
Curated Selection
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