P2X4 antagonist-1
P2X4 antagonist-1 (Compound 24) is an antagonist for P2X4 with IC50 of 15 nM[1].
Product Specifications
CAS Number
2055601-42-6
UNSPSC
12352005
Target
P2X Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/p2x4-antagonist-1.html
Purity
99.89
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=CC=CC(OC2=C(S(=O)(N)=O)C=C(NC(CC3=C(Cl)C=CC=C3Cl)=O)C=C2)=C1
Molecular Formula
C20H15Cl3N2O4S
Molecular Weight
485.77
References & Citations
[1]Werner S, et al., Discovery and characterization of the potent and selective P2X4 inhibitor N-[4- (3-Chlorophenoxy) -3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and structure-guided amelioration of its CYP3A4 induction profile[J]. Journal of Medicinal Chemistry, 2019, 62 (24) : 11194-11217.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2X4 Receptor
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TP760582 50 µg
C13orf30 (FAM216B) (NM_182508) Human Recombinant Protein
Sign In for Pricing
View Details 
