DRAK2-IN-1

DRAK2-IN-1, compound 16, is a potent, selective and ATP-competitive DRAK2 inhibitor with IC50and Kivalues of 3 nM and 0.26 nM, respectively. DRAK2-IN-1 also has inbitory effect on DRAK1 (IC50=51 nM) [1].

Product Specifications

CAS Number

[871837-60-4]

UNSPSC

12352005

Target

DAPK

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/drak2-in-1.html

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCC(NC1=CC2=C(NC(/C2=C3NC4=C(C=CC=C4)C\3=N\O)=O)C=C1)=O

Molecular Formula

C21H20N4O3

Molecular Weight

376.41

References & Citations

[1]Jung ME, et al.Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening.Bioorg Med Chem Lett. 2016 Jun 1;26 (11) :2719-23