Morusin

Morusin is a prenylated flavonoid isolated from Morus alba Linn. with various biological activities, such as antitumor, antioxidant, and anti-bacteria property. Morusin could inhibit NF-κB and STAT3 activity.

Product Specifications

CAS Number

[62596-29-6]

Product Name Alternative

Mulberrochromene

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; NF-κB; STAT

Type

Natural Products

Related Pathways

Anti-infection; JAK/STAT Signaling; NF-κB; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Morusin.html

Concentration

10mM

Purity

99.94

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C1C2=C(O)C=C3C(C=CC(C)(C)O3)=C2OC(C4=CC=C(O)C=C4O)=C1C/C=C(C)\C

Molecular Formula

C25H24O6

Molecular Weight

420.45

Precautions

H302, H315, H319, H335

References & Citations

[1]Li H, et al. Morusin suppresses breast cancer cell growth in vitro and in vivo through C/EBPβ and PPARγ mediated lipoapoptosis. J Exp Clin Cancer Res. 2015 Nov 4;34:137.|[2]Lee JC, et al. Morusin induces apoptosis and suppresses NF-kappaB activity in human colorectal cancer HT-29 cells. Biochem Biophys Res Commun. 2008 Jul 18;372 (1) :236-42.|[3]Lim SL, et al. Morusin induces cell death through inactivating STAT3 signaling in prostate cancer cells. Am J Cancer Res. 2014 Dec 15;5 (1) :289-99.