GPR35 agonist 1
GPR35 agonist 1 (compound 50) is a potent and specific G protein-coupled receptor-35 (GPR35) /CXCR8 agonist with an EC50 of 5.8 nM, displays good agentgability[1].
Product Specifications
CAS Number
2079880-92-3
UNSPSC
12352005
Target
CXCR; GPR35
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Endocrinology
Assay Protocol
https://www.medchemexpress.com/gpr35-agonist-1.html
Purity
99.22
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1OC2=C([N+]([O-])=O)C(O)=C(Br)C=C2C=C1C3=NN=NN3
Molecular Formula
C10H4BrN5O5
Molecular Weight
354.07
References & Citations
[1]Wei L, et al. Discovery of 2H-Chromen-2-one Derivatives as G Protein-Coupled Receptor-35 Agonists. J Med Chem. 2017 Jan 12;60 (1) :362-372.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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