G-Protein antagonist peptide (TFA)
Product Specifications
UNSPSC Description
G-Protein antagonist peptide TFA is a truncated substance P-related peptide, competes with receptor for G protein binding. G-Protein antagonist peptide TFA inhibits the activation of Gi or Go by M2 muscarinic cholinergic receptor (M2 mAChR) or of Gs by beta-adrenergic receptor in the reconstituted phospholipid vesicles, assayed by receptor-promoted GTP hydrolysis[1].
Target Antigen
Adrenergic Receptor; mAChR
Type
Peptides
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/g-protein-antagonist-peptide-tfa.html
Purity
98.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CSCC[C@@H](C(N)=O)NC([C@@H](CC1=CNC2=C1C=CC=C2)NC([C@@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CC5=CC=CC=C5)NC([C@@H](CC6=CNC7=C6C=CC=C7)NC([C@H](CCC(N)=O)NC([C@H](CC8)NC8=O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F
Molecular Weight
1207.28
References & Citations
[1]Mukai H, et al. G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J Biol Chem. 1992;267(23):16237-16243.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, stored under nitrogen, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1376A/G-Protein-antagonist-peptide-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1376A/G-Protein-antagonist-peptide-TFA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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