Thiamine-13C3 (hydrochloride)

Thiamine-13C3 (hydrochloride) is the 13C-labeled Thiamine (hydrochloride) . Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

Product Specifications

Product Name Alternative

Thiamine chloride-13C3 (hydrochloride) ; Vitamin B1-13C3 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Endogenous Metabolite; HBV; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Apoptosis; Metabolic Enzyme/Protease; Others

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/thiamine-13c3-hydrochloride.html

Purity

99.90

Solubility

10 mM in DMSO|DMSO : 6.67mg/mL (ultrasonic) |H2O : 100mg/mL (ultrasonic)

Smiles

[13CH3][13C]1=[13C](CCO)SC=[N+]1CC2=CN=C(C)N=C2N.[Cl-].Cl

Molecular Formula

C9 13C3H18Cl2N4OS

Molecular Weight

340.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Moulin M, et al. Analysis of Chlamydomonas thiamin metabolism in vivo reveals riboswitch plasticity. Proc Natl Acad Sci U S A. 2013 Sep 3;110 (36) :14622-7.