HDAC-IN-40

HDAC-IN-40 is a potent alkoxyamide-based HDAC inhibitor with Ki values of 60 nM and 30 nM for HDAC2 and HDAC6, respectively. HDAC-IN-40 had antitumor effects[1].

Product Specifications

CAS Number

[2463198-51-6]

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hdac-in-40.html

Purity

98.71

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(NOCCCCCC(NO)=O)C1=CC(OC)=CC(OC)=C1

Molecular Formula

C15H22N2O6

Molecular Weight

326.34

References & Citations

[1]Yodita Asfaha, et al. Novel alkoxyamide-based histone deacetylase inhibitors reverse cisplatin resistance in chemoresistant cancer cells. Bioorg Med Chem. 2020 Jan 1;28 (1) :115108.