HDAC-IN-40
HDAC-IN-40 is a potent alkoxyamide-based HDAC inhibitor with Ki values of 60 nM and 30 nM for HDAC2 and HDAC6, respectively. HDAC-IN-40 had antitumor effects[1].
Product Specifications
CAS Number
[2463198-51-6]
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac-in-40.html
Purity
98.71
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NOCCCCCC(NO)=O)C1=CC(OC)=CC(OC)=C1
Molecular Formula
C15H22N2O6
Molecular Weight
326.34
References & Citations
[1]Yodita Asfaha, et al. Novel alkoxyamide-based histone deacetylase inhibitors reverse cisplatin resistance in chemoresistant cancer cells. Bioorg Med Chem. 2020 Jan 1;28 (1) :115108.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC2; HDAC4; HDAC6; HDAC8
Available Sizes
Curated Selection
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