Nucleoside-Analog-2

Nucleoside-Analog-2 is a 4'-Azidocytidine analogue against Hepatitis C virus (HCV) replication. Nucleoside-Analog-2 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

876708-01-9

UNSPSC

12352005

Target

HCV; Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Nucleoside-Analog-2.html

Purity

95.0

Solubility

DMSO : 33.33 mg/mL (ultrasonic) |H2O : 20 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@](CO)(N=[N+]=[N-])O[C@@H](N2C(NC(C=C2)=O)=O)[C@H]1O

Molecular Formula

C9H11N5O6

Molecular Weight

285.21

References & Citations

[1]Smith DB, et al. The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine. J Med Chem. 2009 Jan 8;52 (1) :219-23.