FT011

FT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis[1]. FT011 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[1001288-58-9]

Product Name Alternative

Asengeprast

UNSPSC

12352005

Hazard Statement

H315, H319

Target

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/FT011.html

Purity

99.32

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CC=C1NC(/C=C/C2=CC=C(C(OC)=C2)OCC#C)=O)O

Molecular Formula

C20H17NO5

Molecular Weight

351.35

Precautions

H315, H319

References & Citations

[1]Zhang Y, et al. A new anti-fibrotic drug attenuates cardiac remodeling and systolic dysfunction following experimental myocardial infarction. Int J Cardiol. 2013 Sep 30;168 (2) :1174-85.