Quinizarin
Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM) . Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth[1][2].
Product Specifications
CAS Number
81-64-1
Product Name Alternative
1,4-Dihydroxyanthraquinone
UNSPSC
12171500
Hazard Statement
H410
Target
DNA/RNA Synthesis; Fungal
Type
Dye Reagents
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/quinizarin.html
Purity
98.84
Solubility
DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=C(C=CC=C2)C(C3=C(O)C=CC(O)=C13)=O
Molecular Formula
C14H8O4
Molecular Weight
240.21
Precautions
H410
References & Citations
[1]Verebová V, et al. Anthraquinones quinizarin and danthron unwind negatively supercoiled DNA and lengthen linear DNA. Biochem Biophys Res Commun. 2014;444 (1) :50-55.|[2]Dominic Cheuk, et al. Investigation into solid and solution properties of quinizarin.|[3]Wang M, et al. Electrospun 1,4-DHAQ-doped cellulose nanofiber films for reusable fluorescence detection of trace Cu2+ and further for Cr3+. Environ Sci Technol. 2012;46 (1) :367-373.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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