Quilseconazole
Product Specifications
UNSPSC Description
Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes[1].
Target Antigen
Cytochrome P450; Fungal
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/quilseconazole.html
Purity
98.98
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@](CN1C=NN=N1)(C(C=CC(F)=C2)=C2F)C(F)(C3=CC=C(C4=CC=C(OC(F)(F)F)C=C4)C=N3)F
Molecular Weight
513.37
References & Citations
[1]Lockhart SR, et al. The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2528-31.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-109040/Quilseconazole-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-109040/Quilseconazole-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
1340593-70-5
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
BNC680271-500 500 µL
Anti-CD11b / MAC-1 (Microglial Marker) (ITGAM/271), CF568 conjugate
Ask
View Details ![N-[4-(2-Chloro-acetyl)-phenyl]-propionamide](https://cdn.genprice.uk/genprice/genprice5.png)