Phloretin (Standard)
Phloretin (Standard) is the analytical standard of Phloretin. This product is intended for research and analytical applications. Phloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Malus pumila Mill., has anti-inflammatory activities. Phloridzin is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2) . Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC50values of 49 μM and 61 μM, respectively[1].Phloretin has the potential for the treatment of rheumatoid arthritis (RA) and allergic airway inflammation[4].
Product Specifications
CAS Number
60-82-2
Product Name Alternative
NSC 407292 (Standard) ; RJC 02792 (Standard)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Endogenous Metabolite; GLUT; Reference Standards; SGLT
Type
Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/phloretin-standard.html
Purity
90.000000
Smiles
O=C(C1=C(O)C=C(O)C=C1O)CCC2=CC=C(O)C=C2
Molecular Formula
C15H14O5
Molecular Weight
274.27
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Isoform
GLUT1; GLUT2; Microbial Metabolite; SGLT1; SGLT2
Available Sizes
Frequently Asked Questions
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