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Phloretin (Standard)

Phloretin (Standard) is the analytical standard of Phloretin. This product is intended for research and analytical applications. Phloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Malus pumila Mill., has anti-inflammatory activities. Phloridzin is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2) . Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC50values of 49 μM and 61 μM, respectively[1].Phloretin has the potential for the treatment of rheumatoid arthritis (RA) and allergic airway inflammation[4].

Product Specifications

CAS Number

60-82-2

Product Name Alternative

NSC 407292 (Standard) ; RJC 02792 (Standard)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite; GLUT; Reference Standards; SGLT

Type

Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/phloretin-standard.html

Purity

90.000000

Smiles

O=C(C1=C(O)C=C(O)C=C1O)CCC2=CC=C(O)C=C2

Molecular Formula

C15H14O5

Molecular Weight

274.27

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference Standards

Clinical Information

No Development Reported

Isoform

GLUT1; GLUT2; Microbial Metabolite; SGLT1; SGLT2

Available Sizes

Frequently Asked Questions

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