HENT4-IN-1

HENT4-IN-1 is a potent and selective human ENT4 (equilibrative nucleoside transporter 4) inhibitor with an IC50 of 74.4 nM[1].

Product Specifications

CAS Number

[949467-71-4]

UNSPSC

12352005

Target

Nucleoside Transporters

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hent4-in-1.html

Concentration

10mM

Purity

99.94

Solubility

DMSO : ≥ 125 mg/mL

Smiles

CC(C)CN(C1=NC(NCCO)=NC2=C1N=C(NCCO)N=C2N(CC(C)C)CC(C)C)CC(C)C

Molecular Formula

C26H48N8O2

Molecular Weight

504.71

References & Citations

[1]Wang C, et al. Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4) . Biochem Pharmacol. 2013 Dec 1;86 (11) :1531-40.