UbcH13/Uev1A Protein, Active

<strong>UbcH13/Uev1A Protein, Active</strong>_x000D_ <strong>Catalog number:</strong> B2018852_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> RT_x000D_ <strong>Keywords:</strong> UbcH13 - Ubiquitin-conjugating enzyme E2 N, Bendless-like ubiquitin-conjugating enzyme, Ubiquitin carrier protein N, UBE2N, Ubc13, Uev1A - Ubiquitin-conjugating enzyme E2 variant 1, CROC-1, UBE2V1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Yung C, Sha D, Li L, Chin LS. Parkin Protects Against Misfolded SOD1 Toxicity by Promoting Its Aggresome Formation and Autophagic Clearance Mol Neurobiol. 2016 Nov;53(9):6270-6287._x000D_ 2: Uchiki T, Kim HT, Zhai B, Gygi SP, Johnston JA, O'Bryan JP, Goldberg AL. The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognition J Biol Chem. 2009 May 8;284(19):12622-32._x000D_ 3: Olzmann JA, Li L, Chudaev MV, Chen J, Perez FA, Palmiter RD, Chin LS. Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6 J Cell Biol. 2007 Sep 10;178(6):1025-38._x000D_ 4: Doss-Pepe EW, Chen L, Madura K. Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains J Biol Chem. 2005 Apr 29;280(17):16619-24._x000D_ 5: Kim HT, Kim KP, Lledias F, Kisselev AF, Scaglione KM, Skowyra D, Gygi SP, Goldberg AL. Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages J Biol Chem. 2007 Jun 15;282(24):17375-86._x000D_ 6: Wu Z, Shen S, Zhang Z, Zhang W, Xiao W. Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-–∫B mediated matrix metalloproteinase-1 gene regulation Breast Cancer Res. 2014 Jul 14;16(4):R75._x000D_ 7: Niu T, Wu Z, Xiao W. Uev1A promotes breast cancer cell migration by up-regulating CT45A expression via the AKT pathway BMC Cancer. 2021 Sep 9;21(1):1012._x000D_ 8: Minakawa M, Sone T, Takeuchi T, Yokosawa H. Regulation of the nuclear factor (NF)-kappaB pathway by ISGylation Biol Pharm Bull. 2008 Dec;31(12):2223-7._x000D_ 9: Ordureau A, Smith H, Windheim M, Peggie M, Carrick E, Morrice N, Cohen P. The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1 Biochem J. 2008 Jan 1;409(1):43-52._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/9580084">10: Thomson TM, Khalid H, Lozano JJ, Sancho E, Ari√±o J. Role of UEV-1A, a homologue of the tumor suppressor protein TSG101, in protection from DNA damage FEBS Lett. 1998 Feb 13;423(1):49-52. </a>_x000D_ _x000D_ <strong>Products Related to UbcH13/Uev1A Protein, Active can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>