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NVS-STG2

NVS-STG2 is a molecular glue that targets STING[1][2].

Product Specifications

CAS Number

[3030588-01-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Molecular Glues; STING

Type

Reference compound

Related Pathways

Immunology/Inflammation; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nvs-stg2.html

Purity

99.76

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC1=C(C=CC(C(O)=O)=C1)NCC2=CC=C(C=C2)C3(OCC(C)(CO3)C)C(C)(C)C

Molecular Formula

C25H33NO5

Molecular Weight

427.53

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Li J et al. Activation of human STING by a molecular glue-like compound. Nat Chem Biol. 2023 Oct 12.|[2]Sulpizio A, et al. A new road to STING activation. Nat Chem Biol. 2023 Oct 13.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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