NVS-STG2
NVS-STG2 is a molecular glue that targets STING[1][2].
Product Specifications
CAS Number
[3030588-01-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Molecular Glues; STING
Type
Reference compound
Related Pathways
Immunology/Inflammation; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nvs-stg2.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=C(C=CC(C(O)=O)=C1)NCC2=CC=C(C=C2)C3(OCC(C)(CO3)C)C(C)(C)C
Molecular Formula
C25H33NO5
Molecular Weight
427.53
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Li J et al. Activation of human STING by a molecular glue-like compound. Nat Chem Biol. 2023 Oct 12.|[2]Sulpizio A, et al. A new road to STING activation. Nat Chem Biol. 2023 Oct 13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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