(Rac) -TBAJ-876

(Rac) -TBAJ-876 is a racemate of TBAJ-876. TBAJ-876 is the inhibitor of mycobacterium tuberculosis. TBAJ-876 is the analogue of the anti-tuberculosis agent Bedaquiline (HY-14881) . TBAJ-876 has the potential for the research of tuberculosis[1].

Product Specifications

CAS Number

[2131784-39-7]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/rac-tbaj-876.html

Purity

99.98

Solubility

DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

COC1=NC(OC)=C(OC)C(C(C2=CC(C=C(Br)C=C3)=C3N=C2OC)C(C4=CC(OC)=NC(OC)=C4)(O)CCN(C)C)=C1

Molecular Formula

C31H37BrN4O7

Molecular Weight

657.55

References & Citations

[1]Sutherland HS, et al. Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology. Bioorg Med Chem. 2020 Jan 1;28 (1) :115213.