RC363
RC363 is a novel probucol analog with the activity to protect mouse hippocampal cells and primary cortical neurons from glutamate-induced oxidative cell death (ferroptosis) and increase glutathione peroxidase (GPx) 1 levels and activity.
Product Specifications
CAS Number
[2584411-86-7]
UNSPSC
12352005
Target
Glutathione Peroxidase
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rc363.html
Smiles
OC1=C(C(C)(C)C)C=C(SC2=CC=CS2)C=C1C(C)(C)C
Molecular Formula
C18H24OS2
Molecular Weight
320.51
References & Citations
[1]New Probucol Analogues Inhibit Ferroptosis, Improve Mitochondrial Parameters, and Induce Glutathione Peroxidase in HT22 Cells
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GPX1
Curated Selection
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