Utreglutide

Utreglutide is an effective glucagon-like peptide 1 (GLP-1) receptor agonist. Utreglutide can lower blood pressure, blood lipids and body weight, and improve cardiovascular metabolism. Utreglutide can be used for research on type 2 diabetes or non-type 2 diabetes obesity[1][2].

Product Specifications

CAS Number

[2460862-12-6]

UNSPSC

12352209

Target

GLP Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/utreglutide.html

Purity

98.42

Solubility

DMSO : ≥ 1.25 mg/mL

Smiles

[Utreglutide]

Molecular Formula

C191H298N46O58

Molecular Weight

4166.67

References & Citations

[1]THENNATI R, et al. Effects of Once-Weekly Utreglutide (GL0034) in Individuals with Overweight and Obesity on Lipid Metabolism—A 10-Week Exploratory Proof-of-Concept Study. Diabetes. 2025 Jun 13;74 (Supplement_1) :759-P.|[2]Thennati R, et al. Once Weekly Utreglutide (GL0034), a Glucagon-like Peptide-1 Receptor Agonist, at 4x 450 µg Doses Reduces Blood Pressure, Lipids, and Body Weight in Post-menopausal Females: A Phase I Study. Circulation. 2024 Nov 12;150 (Suppl_1) :A4116298-.