Cysteine thiol probe
Cysteine Thiol Probe is a thiol-based probe designed to label electrophilic natural products. Cysteine Thiol Probe possesses each of the characteristics of an ideal pharmacophore probe, and has a chromophore. Cysteine Thiol Probe is capable of engaging enone-, β-lactam-, and β-lactone-based electrophilic metabolites[1][2].
Product Specifications
CAS Number
1947408-74-3
UNSPSC
12352005
Target
Fluorescent Dye
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cysteine-thiol-probe.html
Purity
98.55
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
SC[C@@H](C(OC)=O)NC(C1=CC=C(Br)C=C1)=O
Molecular Formula
C11H12BrNO3S
Molecular Weight
318.19
References & Citations
[1]Castro-Falcón G, et al. Thiol Probes To Detect Electrophilic Natural Products Based on Their Mechanism of Action. ACS Chem Biol. 2016 Aug 19;11 (8) :2328-36.|[2]Reimer D, et al. Thiol-Based Probe for Electrophilic Natural Products Reveals That Most of the Ammosamides Are Artifacts. J Nat Prod. 2017 Jan 27;80 (1) :126-133.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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