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ZCAN262

ZCAN262 (compound 6) is an AMPA modulator. ZCAN262 prevents AMPA-mediated excitotoxicity by targeting an allosteric binding site[1].

Product Specifications

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/zcan262.html

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

CN(C(C1=NC(N2CC3=CN(N=C3C2)CC4=CC=C(C=C4F)F)=NC=C1)=O)C

Molecular Formula

C19H18F2N6O

Molecular Weight

384.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Dongxu Zhai, et al. Small-molecule targeting AMPA-mediated excitotoxicity has therapeutic effects in mouse models for multiple sclerosis. Sci Adv. 2023, 9, 49.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-163097/ZCAN262-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-163097/ZCAN262-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AMPA Receptor

Available Sizes

Curated Selection

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