LY339434
Product Specifications
UNSPSC Description
LY339434 is a potent and selective agonist for the hydrochloride receptor GluR5. LY339434 affects the rapid death of neurons through n-methyl-D-aspartate (NMDA) receptors[1][2].
Target Antigen
iGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly339434.html
Solubility
10 mM in DMSO
Smiles
N[C@@H](C[C@@H](C/C=C/C1=CC=C2C=CC=CC2=C1)C(O)=O)C(O)=O
Molecular Weight
313.35
References & Citations
[1]Small B, et al. LY339434, a GluR5 kainate receptor agonist. Neuropharmacology. 1998 Oct-Nov;37(10-11):1261-7.|[2]Moldrich RX, et al. Excitotoxic profile of LY339434, a GluR5 agonist, in cultured murine cortical neurons. Brain Res. 2000 Apr 17;862(1-2):270-5.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114550/LY339434-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114550/
Clinical Information
No Development Reported
CAS Number
219566-62-8
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
