LY339434

LY339434 is a potent and selective agonist for the hydrochloride receptor GluR5. LY339434 affects the rapid death of neurons through n-methyl-D-aspartate (NMDA) receptors[1][2].

Product Specifications

CAS Number

[219566-62-8]

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ly339434.html

Solubility

10 mM in DMSO

Smiles

N[C@@H](C[C@@H](C/C=C/C1=CC=C2C=CC=CC2=C1)C(O)=O)C(O)=O

Molecular Formula

C18H19NO4

Molecular Weight

313.35

References & Citations

[1]Small B, et al. LY339434, a GluR5 kainate receptor agonist. Neuropharmacology. 1998 Oct-Nov;37 (10-11) :1261-7.|[2]Moldrich RX, et al. Excitotoxic profile of LY339434, a GluR5 agonist, in cultured murine cortical neurons. Brain Res. 2000 Apr 17;862 (1-2) :270-5.