LY339434
LY339434 is a potent and selective agonist for the hydrochloride receptor GluR5. LY339434 affects the rapid death of neurons through n-methyl-D-aspartate (NMDA) receptors[1][2].
Product Specifications
CAS Number
[219566-62-8]
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly339434.html
Solubility
10 mM in DMSO
Smiles
N[C@@H](C[C@@H](C/C=C/C1=CC=C2C=CC=CC2=C1)C(O)=O)C(O)=O
Molecular Formula
C18H19NO4
Molecular Weight
313.35
References & Citations
[1]Small B, et al. LY339434, a GluR5 kainate receptor agonist. Neuropharmacology. 1998 Oct-Nov;37 (10-11) :1261-7.|[2]Moldrich RX, et al. Excitotoxic profile of LY339434, a GluR5 agonist, in cultured murine cortical neurons. Brain Res. 2000 Apr 17;862 (1-2) :270-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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