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Ipragliflozin (Standard)

Ipragliflozin (Standard) is the analytical standard of Ipragliflozin. This product is intended for research and analytical applications. Ipragliflozin (ASP1941) is an orally active and selective SGLT2 inhibitor with IC50s of 7.38 and 1876 nM, 6.73 and 1166 nM, 5.64 and 1380 nM for human SGLT2 and SGLT1, rat SGLT2 and SGLT1, mouse SGLT2 and SGLT1, respectively. Antidiabetic agent[1].

Product Specifications

CAS Number

761423-87-4

Product Name Alternative

ASP1941 (Standard)

UNSPSC

12352005

Target

Reference Standards; SGLT

Type

Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ipragliflozin-standard.html

Smiles

FC1=CC=C([C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)C=C1CC3=CC(C=CC=C4)=C4S3

Molecular Formula

C21H21FO5S

Molecular Weight

404.45

References & Citations

[1]Atsuo Tahara, et al. Pharmacological profile of ipragliflozin (ASP1941), a novel selective SGLT2 inhibitor, in vitro and in vivo. Naunyn Schmiedebergs Arch Pharmacol. 2012 Apr;385 (4) :423-36.|[2]Shiho Komatsu, et al. SGLT2 inhibitor ipragliflozin attenuates breast cancer cell proliferation. Endocr J. 2020 Jan 28;67 (1) :99-106.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Isoform

SGLT2

Available Sizes

Frequently Asked Questions

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