MTDH antibody
Product Specifications
Background
MTDH, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22, the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma, and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression. This antibody got two bands about 70 kDa and 80 kDa in western blotting, possibly due to posttranslational modification. This antibody is specific to AEG-1/MTDH.
Synonyms
Protein LYRIC|3D3/LYRIC|Astrocyte elevated gene-1 protein (AEG-1) |Lysine-rich CEACAM1 co-isolated protein|Metadherin|Metastasis adhesion protein|MTDH|AEG1|LYRIC
Gene ID
92140
UniProt
Q86UE4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Metadherin
Target
MTDH
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cancer
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
64-80 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
168-298
Curated Selection
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