RKH (acetate)
RKH acetate exerts protective effects against sepsis-induced death and organ damage. RKH acetate can directly bind to Toll-like receptor 4 (TLR4) and block TLR4 signal transduction in immune cells[1].
Product Specifications
UNSPSC
12352209
Target
Toll-like Receptor (TLR)
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rkh-acetate.html
Purity
99.79
Solubility
H2O : ≥ 30 mg/mL|DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CCCCN)C(N[C@@H](CC1=CNC=N1)C(O)=O)=O)[C@H](CCCNC(N)=N)N.O=C(O)C.[x]
Molecular Formula
C18H33N9O4.xC2H4O2
Molecular Weight
439.51 (free acid)
References & Citations
[1]Shihao Xie, et al. Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis. Gut. 2023 Dec 7;73 (1) :78-91.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
TLR4
Available Sizes
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