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N-ε-propargyloxycarbonyl-L-lysine

N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys (Poc) -OH) is a lysine-based unnatural amino acid (UAA) . N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals[1][2]. N-ε-propargyloxycarbonyl-L-lysine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[1215204-46-8]

Product Name Alternative

H-​L-​Lys (Poc) ​-​OH

UNSPSC

12171500

Hazard Statement

H302-H315-H319-H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-ε-propargyloxycarbonyl-l-lysine.html

Purity

98.0

Solubility

H2O : 17.86 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N[C@@H](CCCCNC(OCC#C)=O)C(O)=O

Molecular Formula

C10H16N2O4

Molecular Weight

228.25

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Kyung Jin Lee, et al. Site-Specific Labeling of Proteins Using Unnatural Amino Acids. Mol Cells. 2019 May 31;42 (5) :386-396.|[2]Enke HEIKE, et al. Modified microcystins and nodularins.WO2018206715A2

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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