800CW acid

800CW acid is an orally active near-infrared (NIR) dye (excitation/emission 774/789 nm) . 800CW acid can be used for intestinal permeability testing. 800CW acid can be used for in vivo imaging studies[1][2].

Product Specifications

CAS Number

[1088919-86-1]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/800cw-acid.html

Purity

98.81

Solubility

10 mM in DMSO

Smiles

O=C(CCCCCN1C2=CC=C(S(=O)(O[Na])=O)C=C2C(C)(C)/C1=C/C=C3C(OC4=CC=C(S(=O)(O[Na])=O)C=C4)=C(CCC\3)/C=C/C5=[N+](CCCCS(=O)(O[Na])=O)C6=C(C5(C)C)C=C(S(=O)([O-])=O)C=C6)O[Na]

Molecular Formula

C46H50N2Na4O15S4

Molecular Weight

1091.11

References & Citations

[1]Li Y, et al. Monitoring Tumor Targeting and Treatment Effects of IRDye 800CW and GX1-Conjugated Polylactic Acid Nanoparticles Encapsulating Endostar on Glioma by Optical Molecular Imaging. Mol Imaging. 2015;14:356-65.|[2]Zhang L, et al. Near infrared readouts offer sensitive and rapid assessments of intestinal permeability and disease severity in inflammatory bowel disease models. Sci Rep. 2020 Mar 13;10 (1) :4696.