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L-Phenylalanine-d5

Product Specifications

UNSPSC Description

L-Phenylalanine-d5 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

Target Antigen

Calcium Channel; Endogenous Metabolite; iGluR

Type

Isotope-Labeled Compounds

Related Pathways

Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Purity

99.15

Solubility

H2O : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

OC([C@@H](N)CC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O

Molecular Weight

170.22

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Clinical Information

No Development Reported

CAS Number

56253-90-8

Available Sizes

Curated Selection

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