L-Phenylalanine-d5
L-Phenylalanine-d5 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S) -2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
Product Specifications
CAS Number
[56253-90-8]
Product Name Alternative
(S) -2-Amino-3-phenylpropionic acid-d5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Calcium Channel; Endogenous Metabolite; iGluR
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Concentration
10mM
Purity
99.90
Solubility
H2O : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC([C@@H](N)CC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O
Molecular Formula
C9H6D5NO2
Molecular Weight
170.22
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
Explore Other Products
Browse additional items from our catalog
Magea10 sgRNA CRISPR Lentivector (Mouse) (Target 1)
Recombinant Human TNFRSF19 / TROY Protein (His tag)