Siastatin B
Siastatin B is an effective broad-spectrum glycosidase inhibitor that can effectively inhibit the activities of sialidase, β-D-glucuronidase, N-acetyl-glucosaminidase, β-glucuronidase, and human heparinase[1][2].
Product Specifications
CAS Number
54795-58-3
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Endogenous Metabolite; β-glucuronidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/siastatin-b.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1CN[C@H](NC(C)=O)[C@@H](O)[C@H]1O)O
Molecular Formula
C8H14N2O5
Molecular Weight
218.21
Precautions
H315, H319, H335
References & Citations
[1]Chen Y, et al. Molecular Basis for Inhibition of Heparanases and β-Glucuronidases by Siastatin B. J Am Chem Soc. 2024 Jan 10;146 (1) :125-133.|[2]Chen Y, et al. Molecular Basis for Inhibition of Heparanases and β-Glucuronidases by Siastatin B[J]. Journal of the American Chemical Society, 2023.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
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