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Siastatin B

Siastatin B is an effective broad-spectrum glycosidase inhibitor that can effectively inhibit the activities of sialidase, β-D-glucuronidase, N-acetyl-glucosaminidase, β-glucuronidase, and human heparinase[1][2].

Product Specifications

CAS Number

54795-58-3

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite; β-glucuronidase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/siastatin-b.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1CN[C@H](NC(C)=O)[C@@H](O)[C@H]1O)O

Molecular Formula

C8H14N2O5

Molecular Weight

218.21

Precautions

H315, H319, H335

References & Citations

[1]Chen Y, et al. Molecular Basis for Inhibition of Heparanases and β-Glucuronidases by Siastatin B. J Am Chem Soc. 2024 Jan 10;146 (1) :125-133.|[2]Chen Y, et al. Molecular Basis for Inhibition of Heparanases and β-Glucuronidases by Siastatin B[J]. Journal of the American Chemical Society, 2023.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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