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Quercetagitrin (Standard)

Quercetagitrin (Standard) is the analytical standard of Quercetagitrin. This product is intended for research and analytical applications. Quercetagitrin (Quercetagetin-7-O-glucoside) is a natural product that can be isolated from the African marigold (Tagetes erecta) . Quercetagitrin has anti-inflammatory activity. Quercetagitrin inhibits Tau accumulation. Quercetagitrin can reverse neuroinflammation and cognitive deficits in P301S-Tau transgenic mouse model through inhibiting NF-κB activation. Quercetagitrin is a dual-target inhibitor of PTPN6 (IC50 = 1 μM) and PTPN9 (IC50 = 1.7 μM) . Quercetagitrin enhances glucose uptake by mature C2C12 myoblasts. Quercetagitrin can be studied in research for Alzheimer’s disease and type 2 diabetes[1][2][3][4].

Product Specifications

CAS Number

548-75-4

Product Name Alternative

Quercetagetin-7-O-glucoside (Standard)

UNSPSC

12352005

Target

NF-κB; Phosphatase; Reference Standards; Tau Protein

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/quercetagitrin-standard.html

Smiles

O=C1C2=C(O)C(O)=C(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)CO)C=C2OC(C4=CC(O)=C(O)C=C4)=C1O

Molecular Formula

C21H20O13

Molecular Weight

480.38

References & Citations

[1]BY P. SURYAPRAKASA RAO, et al. Isolation and constitution of quercetagitrin, a glucoside of quercetagetin. Proceedings of the Indian Academy of Sciences - Section A. 1941.|[2]Tordera M, et al. Influence of anti-inflammatory flavonoids on degranulation and arachidonic acid release in rat neutrophils. Z Naturforsch C. 1994 Mar-Apr;49 (3-4) :235-40.|[3]Zhong, S., et al., (2023) . Quercetagitrin Inhibits Tau Accumulation and Reverses Neuroinflammation and Cognitive Deficits in P301S-Tau Transgenic Mice. Molecules (Basel, Switzerland), 28 (9), 3964. |[4]Gone, G. B., et al., (2024) . Exploring the Anti-Diabetic Potential of Quercetagitrin through Dual Inhibition of PTPN6 and PTPN9. Nutrients, 16 (5), 647.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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