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Perfluorohexane

Perfluorohexane (AF-0150) is a perfluorocarbon. Perfluorohexane is also an enhancer of high-intensity focused ultrasound (HIFU) therapy. Perfluorohexane increases HO-1 and IL-10. Perfluorohexane exerts an antioxidant effect. Perfluorohexane alleviates lung injury induced by LPS. Perfluorohexane improves the efficiency and precision of treatment and reduces damage to surrounding normal tissues. Perfluorohexane can be used in the study of acute lung injury[1][2][3].

Product Specifications

CAS Number

355-42-0

Product Name Alternative

AF-0150

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Heme Oxygenase (HO) ; Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Purity

98.62

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(F)(C(F)(C(F)(C(F)(C(F)(C(F)(F)F)F)F)F)F)F

Molecular Formula

C6F14

Molecular Weight

338.04

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang X, et al. Perfluorohexane‐encapsulated mesoporous silica nanocapsules as enhancement agents for highly efficient high intensity focused ultrasound (HIFU) [J]. Advanced Materials, 2012, 6 (24) : 785-791.|[2]Ge ZJ, et al. Systemic perfluorohexane attenuates lung injury induced by lipopolysaccharide in rats: the role of heme oxygenase-1. Pharmacol Rep. 2010 Jan-Feb;62 (1) :170-7.|[3]Haufe D, et al. Effect of perfluorohexane on the expression of cellular adhesion molecules and surfactant protein A in human mesothelial cells in vitro. Artif Cells Blood Substit Immobil Biotechnol. 2011 Aug;39 (4) :239-46.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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