Perfluorohexane

Perfluorohexane (AF-0150) is a perfluorocarbon. Perfluorohexane is also an enhancer of high-intensity focused ultrasound (HIFU) therapy. Perfluorohexane increases HO-1 and IL-10. Perfluorohexane exerts an antioxidant effect. Perfluorohexane alleviates lung injury induced by LPS (HY-D1056A1) . Perfluorohexane improves the efficiency and precision of treatment and reduces damage to surrounding normal tissues. Perfluorohexane can be used in the study of acute lung injury[1][2][3].

Product Specifications

CAS Number

[355-42-0]

Product Name Alternative

AF-0150

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Heme Oxygenase (HO) ; Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Purity

98.62

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(F)(C(F)(C(F)(C(F)(C(F)(C(F)(F)F)F)F)F)F)F

Molecular Formula

C6F14

Molecular Weight

338.04

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang X, et al. Perfluorohexane‐encapsulated mesoporous silica nanocapsules as enhancement agents for highly efficient high intensity focused ultrasound (HIFU) [J]. Advanced Materials, 2012, 6 (24) : 785-791.|[2]Ge ZJ, et al. Systemic perfluorohexane attenuates lung injury induced by lipopolysaccharide in rats: the role of heme oxygenase-1. Pharmacol Rep. 2010 Jan-Feb;62 (1) :170-7.|[3]Haufe D, et al. Effect of perfluorohexane on the expression of cellular adhesion molecules and surfactant protein A in human mesothelial cells in vitro. Artif Cells Blood Substit Immobil Biotechnol. 2011 Aug;39 (4) :239-46.