1-Deoxynojirimycin (hydrochloride)
Product Specifications
UNSPSC Description
1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin hydrochloride suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin hydrochloride possesses antihyperglycemic, anti-obesity, and antiviral features[1][2].
Target Antigen
Antibiotic; Bacterial; Glycosidase; PI3K
Type
Natural Products
Related Pathways
Anti-infection;Metabolic Enzyme/Protease;PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/1-deoxynojirimycin-hydrochloride.html
Solubility
H2O : 250 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@@H](CO)NC[C@H](O)[C@H]1O.[H]Cl
Molecular Weight
199.63
References & Citations
[1]Gao K, et al. 1-Deoxynojirimycin: Occurrence, Extraction, Chemistry, Oral Pharmacokinetics, Biological Activities and In Silico Target Fishing. Molecules. 2016 Nov 23;21(11). pii: E1600.|[2]Chaluntorn Vichasilp,et al. Development of high 1-deoxynojirimycin (DNJ) content mulberry tea and use of response surface methodology to optimize tea-making conditions for highest DNJ extraction. LWT - Food Science and Technology. Volume 45, Issue 2, March 2012, Pages 226-232.|[3]Liu Q, et al. 1-Deoxynojirimycin Alleviates Insulin Resistance via Activation of Insulin Signaling PI3K/AKT Pathway in Skeletal Muscle of db/db Mice. Molecules. 2015 Dec 4;20(12):21700-14.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14860A/1-Deoxynojirimycin-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14860A/1-Deoxynojirimycin-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
73285-50-4
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
