ALDH1A3-IN-1

ALDH1A3-IN-1 (Compound 14) is a potent ALDH1A3 inhibitor, with an IC50 of 0.63 μM and a Ki of 0.46 μM. ALDH1A3-IN-1 can be studied in prostate cancer[1].

Product Specifications

CAS Number

[1695970-90-1]

UNSPSC

12352005

Target

Aldehyde Dehydrogenase (ALDH)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aldh1a3-in-1.html

Concentration

10mM

Purity

98.05

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=CC1=CC(Br)=C(C=C1)N(CCC)CCC

Molecular Formula

C13H18BrNO

Molecular Weight

284.19

References & Citations

[1]Ali I M Ibrahim, et al. Expansion of the 4- (Diethylamino) benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65 (5) :3833-3848.