ADTL-SA1215
ADTL-SA1215 is a first-in-class specific small-molecule activator of SIRT3 that modulates autophagy in triple negative breast cancer.
Product Specifications
CAS Number
[782387-91-1]
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/adtl-sa1215.html
Purity
98.96
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C(CCCC)OC2=CC=CC=C12)C3=CC(I)=C(OCCCN4CCCC4)C(I)=C3
Molecular Formula
C26H29I2NO3
Molecular Weight
657.32
References & Citations
[1]Zhang J, et al. Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer. J Med Chem. 2021 Oct 14;64 (19) :14192-14216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MR211243L3V 200 µL
EmL4 (BC065178) Mouse Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 
MBS6398848-01 0.1 mL
YAP1 (65kD Yes-associated Protein, YAP65, Yorkie Homolog) (MaxLight 405)
Sign In for Pricing
View Details MBS6398848-02 5x 0.1 mL
YAP1 (65kD Yes-associated Protein, YAP65, Yorkie Homolog) (MaxLight 405)
Sign In for Pricing
View Details 
G1049 96 Tests
Probable crossover junction endonuclease EME2 (EME2) Mouse ELISA Kit
Sign In for Pricing
View Details