L-739758
L-739758 is an antagonist for αIIbβ3 integrin (platelet glycoprotein IIb/IIIa) . L-739758 acts as a peptidomimetic, binds to αIIbβ3 integrin by mimicking the interaction of the RGD (arginine-glycine-aspartic acid) motif, and is involved in the blood coagulation process. L-739758 inhibits platelet aggregation, and is used for thrombosis research[1].
Product Specifications
CAS Number
168157-33-3
UNSPSC
12352005
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-739758.html
Smiles
O=C([C@H](CNC(C1=CC2=C(SC(CCC3CCNCC3)=C2)S1)=O)NS(=O)(C4=CC=CN=C4)=O)O
Molecular Formula
C22H26N4O5S3
Molecular Weight
522.66
References & Citations
[1]Kóňa J. Comparative study of interaction energies between α IIb β 3 integrin and the peptidic, peptidomimetic and non-peptidic ligands by quantum mechanics FMO-PIEDA calculations[J]. Chemical Papers, 2023, 77 (10) : 5913-5930.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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