Tilianin

Tilianin is an active flavonoid glycoside found in many medical plants, with potential anti-hypertensive, myocardial-protective, anti-diabetic, anti-hyperlipidemic, anti-inflammatory and antioxidant effects[1][2][3].

Product Specifications

CAS Number

[4291-60-5]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/tilianin.html

Concentration

10mM

Purity

99.67

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)CO)C=C2OC(C4=CC=C(OC)C=C4)=C1

Molecular Formula

C22H22O10

Molecular Weight

446.40

Precautions

H315, H319

References & Citations

[1]Sergienko TO, et al. Moldavoside--new flavonoid glycoside of Dragocephalum moldavicum L. Farm Zh. 1968;23 (2) :75-8.|[2]Yonghong Zhang , et al. Role of Tilianin against Acute Lung Injury in In Vitro LPS-Induced Alveolar Macrophage Cells and an In Vivo C57BL/6 Mice Model. J Environ Pathol Toxicol Oncol. 2020;39 (4) :335-344.|[3]Liping Wang, et al. Simultaneous determination of tilianin and its metabolites in mice using ultra-high-performance liquid chromatography with tandem mass spectrometry and its application to a pharmacokinetic study. Biomed Chromatogr. 2018 Apr;32 (4) .