BB-Cl-Amidine
Product Specifications
UNSPSC Description
BB-Cl-Amidine is a peptidylarginine deminase (PAD) inhibitor.
Target Antigen
Protein Arginine Deiminase
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/BB-Cl-Amidine.html
Purity
95.03
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C3=NC4=CC=CC=C4N3)CCCNC(CCl)=N
Molecular Weight
459.97
References & Citations
[1]Knight JS, et al. Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice. Ann Rheum Dis. 2015 Dec;74(12):2199-206.Cell Physiol Biochem. 2024 Feb 19;58(1):63-82.|Nat Cell Biol. 2021 Oct 6.|Nat Commun. 2024 Sep 3;15(1):7654.|Oncol Rep. 2023 Jul;50(1):146.|Res Sq. 2024 Jun 04.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111347/BB-Cl-Amidine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111347/BB-Cl-Amidine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1802637-39-3
Available Sizes
Curated Selection
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