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Tert-Butyl 5-bromoisoindoline-2-carboxylate

Tert-Butyl 5-bromoisoindoline-2-carboxylate (Tert-butyl 5-bromo-1,3-dihydro-2H-isoindole-2- carboxylate) is a PROTAC Linker. tert-Butyl 5-bromoisoindoline-2-carboxylate can be used in synthesis PTOTAC HSD17B13 degrader 1 (HY-159651) [1].

Product Specifications

CAS Number

[201940-08-1]

Product Name Alternative

Tert-butyl 5-bromo-1,3-dihydro-2H-isoindole-2- carboxylate

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tert-butyl-5-bromoisoindoline-2-carboxylate.html

Purity

99.78

Smiles

CC(C)(OC(N1CC2=CC=C(Br)C=C2C1)=O)C

Molecular Formula

C13H16BrNO2

Molecular Weight

298.18

Precautions

H302, H315, H319, H335

References & Citations

[1]3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF. WO2024127297.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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