Cis-Piperidine-2,3-dicarboxylic acid

Cis-piperidine-2,3-dicarboxylic acid is a non-specific antagonist of NMDA, AMPA and kainate ionotropic receptors and a partial agonist for NMDA receptors. Cis-piperidine-2,3-dicarboxylic acid can be used in blocking general excitatory synaptic transmissions[1].

Product Specifications

CAS Number

[46026-75-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cis-piperidine-2-3-dicarboxylic-acid.html

Purity

98.0

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(O)[C@H]1NCCC[C@H]1C(O)=O

Molecular Formula

C7H11NO4

Molecular Weight

173.17

Precautions

H302, H315, H319, H335

References & Citations

[1]Viswanathan S, et al. Inner-retinal contributions to the photopic sinusoidal flicker electroretinogram of macaques. Macaque photopic sinusoidal flicker ERG. Doc Ophthalmol. 2002 Sep;105 (2) :223-42.