N-DBCO-N-bis (PEG2-C2-NHS ester)
N-DBCO-N-bis (PEG2-C2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-DBCO-N-bis (PEG2-C2-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Product Specifications
CAS Number
[2128735-29-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-dbco-n-bis-peg2-c2-nhs-ester.html
Purity
96.0
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(N(CCOCCOCCC(ON(C4=O)C(CC4)=O)=O)CCOCCOCCC(ON(C5=O)C(CC5)=O)=O)=O
Molecular Formula
C41H46N4O14
Molecular Weight
818.82
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
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